Across TCGA patient cohorts, GP1BB protein abundance is significantly associated with the RNA expression of many other genes, with 2,556 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GP1BB-associated genes across cancer lineages are HBB, HBA2, and CXCR1. Each is linked with GP1BB in more than 6 cancer types. Because this analysis shows association rather than direction, both GP1BB-to-partner and partner-to-GP1BB results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GP1BB→partner) and Y-score (partner→GP1BB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HBB →	+2.085	+1.079	.006	.001	3	7
CCRCC	HBA2 →	+1.734	+0.747	.004	<.001	3	6
PDAC	CXCR1 →	+1.011	+1.057	<.001	.001	3	5
GBM	PPBP →	+1.507	+0.832	<.001	<.001	3	5
GBM	PF4 →	+1.140	+0.812	<.001	<.001	3	5
CCRCC	FOS →	+1.733	+0.813	.004	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,556 associations by consensus.

Exploration

GP1BB survival (RNA) · tumor vs normal (RNA) · all GP1BB data types