Across TCGA pan-cancer cohorts, GP1BA mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GP1BA data layer compared with 21 for mass-spec protein and 6 for mutation status.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GP1BA mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GP1BA expression acts as an unfavorable survival marker.
UCEC, LSCC, and LUAD are the cancer types where GP1BA mass-spec protein most reproducibly stratifies survival.
mass-spec protein survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.