GP1BA

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GP1BA mutation is significantly associated with the RNA expression of many other genes, with 2,460 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GP1BA-associated genes across cancer lineages are TAF9, TUBGCP5, and FRG1HP. Each is linked with GP1BA in more than 1 cancer types. Because this analysis shows association rather than direction, both GP1BA-to-partner and partner-to-GP1BA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GP1BA→partner) and Y-score (partner→GP1BA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTAF9 →+0.677+2.459<.001<.00132
UCECTUBGCP5 →+0.399+2.550.001<.00132
UCECFRG1HP →+0.697+2.970<.001<.00132
UCECZNF852 →+0.274+2.111.008.00332
UCECTCAIM →+0.374+2.102.003.00132
UCECC5orf24 →+0.463+1.736.006.00732
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,460 associations by consensus.

Exploration