Across TCGA cell cohorts, GP1BA mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GP1BA-associated genes across cancer lineages are USP29, RTL4, and SLC5A5. Each is linked with GP1BA in more than 1 cancer types. Because this analysis shows association rather than direction, both GP1BA-to-partner and partner-to-GP1BA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GP1BA→partner) and Y-score (partner→GP1BA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	USP29 →	+0.025	+3.927	<.001	.004	3	1
BLOOD_Lymphoma	RTL4 →	+0.069	+3.714	<.001	.006	3	1
LARGE_INTESTINE	SLC5A5 →	+0.418	+3.453	<.001	.009	3	1
LARGE_INTESTINE	TSKS →	+0.180	+3.807	.008	.003	3	1
LARGE_INTESTINE	PPEF2 →	+0.045	+4.058	<.001	.001	3	1
LARGE_INTESTINE	GSG1L2 →	+0.013	+4.022	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

Exploration

GP1BA survival (RNA) · tumor vs normal (RNA) · all GP1BA data types