GOT2P7

Across TCGA pan-cancer cohorts, GOT2P7 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of GOT2P7’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GOT2P7 RNA is repressed in tumor relative to normal tissue. In most cancer types GOT2P7 is over-expressed in tumor, although a few such as THCA and LUSC show the opposite, repressed pattern.

THCA, LUSC, and KICH are the cancer types where GOT2P7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOT2P7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	II,III,IV	−0.054	.005	6	view →
LUSC	All	All	−0.043	<.001	5	view →
KICH	Female	III,IV	−0.043	.034	1	view →
KIRP	All	All	−0.015	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

GOT2P7–THCA

Open the THCA breakdown →