GOT2P5

Across TCGA pan-cancer cohorts, GOT2P5 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated GOT2P5 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher GOT2P5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GOT2P5 expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

THCA, BLCA, and KICH are the cancer types where GOT2P5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.180	0.945	<.001	117	view →
BLCA	DFS	Tertile	All	0.122	0.626	.001	72	view →
KICH	OS	Tertile	All	0.161	0.881	<.001	72	view →
STAD	OS	Tertile	All	0.142	0.730	<.001	54	view →
ESCA	DFS	Tertile	III,IV	1.000	0.273	.018	30	view →
HNSC	DFS	Tertile	All	0.436	0.711	.018	24	view →
KIRP	OS	Tertile	All	0.275	0.710	.034	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GOT2P5–THCA (OS)

Open the THCA breakdown →