GOT2P3

Across TCGA pan-cancer cohorts, GOT2P3 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated GOT2P3 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher GOT2P3 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GOT2P3 expression acts as an unfavorable survival marker, although some lineages such as READ and ACC show a favorable association.

READ, ACC, and UCEC are the cancer types where GOT2P3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Quartile	II,III,IV	0.822	0.321	.003	49	view →
ACC	DFS	Tertile	III,IV	0.639	0.096	.001	41	view →
UCEC	DFS	Median	All	0.791	0.879	.003	38	view →
COAD	DFS	Tertile	IV	0.670	0.250	.007	25	view →
KIRC	OS	Quartile	All	0.781	0.546	<.001	24	view →
HNSC	OS	Quartile	All	0.648	0.868	.005	22	view →
STAD	DFS	Median	II,III,IV	0.468	0.590	.013	20	view →
KIRP	DFS	Tertile	All	0.913	0.796	.011	17	view →
THCA	DFS	Median	II,III,IV	0.943	0.789	.008	16	view →
LGG	OS	Median	All	0.749	0.910	<.001	12	view →
MESO	OS	Tertile	All	0.695	0.342	.019	9	view →
OV	OS	Quartile	III,IV	0.650	0.735	.039	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

GOT2P3–READ (DFS)

Open the READ breakdown →