GOT2P2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOT2P2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,913 significant associations in total. OV shows the largest number of these associations.

The most reproducible GOT2P2-associated GO terms across cancer lineages are mRNA modification, Negative regulation of telomere maintenance, and Ribosome-associated ubiquitin-dependent protein catabolic process. Each is linked with GOT2P2 in more than 24 cancer types. Because this analysis shows association rather than direction, both GOT2P2-to-partner and partner-to-GOT2P2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA modification grouped by GOT2P2-low versus GOT2P2-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GOT2P2→partner) and Y-score (partner→GOT2P2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
DLBCmRNA modification →+0.067+1.029<.001<.001325
DLBCNegative regulation of telomere maintenance →+0.063+0.807<.001<.001325
DLBCRibosome-associated ubiquitin-dependent protein catabolic process →+0.079+0.949<.001<.001325
UCSMitochondrial translational elongation →+0.092+0.441<.001<.001324
UCSProtein localization to chromosome, telomeric region →+0.055+0.423.001<.001225
DLBCNegative regulation of telomere maintenance via telomerase →+0.057+0.778<.001<.001324
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,913 associations by consensus.

mRNA modification by GOT2P2 expression — DLBC

Box plot of mRNA modification in GOT2P2-low vs GOT2P2-high samples in DLBC.

Explore this box plot interactively →

Exploration