GOT1

Across TCGA patient cohorts, GOT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,234 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GOT1-associated proteins across cancer lineages are MKI67, CACYBP, and ZYX. Each is linked with GOT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GOT1-to-partner and partner-to-GOT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GOT1 versus MKI67 in BRCA, with a Pearson correlation of 0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GOT1→partner) and Y-score (partner→GOT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MKI67 →	+0.674	+0.408	<.001	.001	3	6
LSCC	CACYBP →	+0.353	+0.758	<.001	<.001	3	5
GBM	ZYX →	-0.398	-0.447	<.001	<.001	3	5
OV	LRCH4 →	-0.259	-0.547	.002	<.001	3	5
PDAC	ATPAF1 →	+0.406	+0.341	.004	.008	3	5
PDAC	SVEP1 →	-0.541	-0.498	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,234 associations by consensus.

GOT1 vs MKI67 — BRCA

Explore this scatter interactively →