GOSR1

Across TCGA patient cohorts, GOSR1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,924 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GOSR1-associated proteins across cancer lineages are GIT1, LIG3, and RHOT1. Each is linked with GOSR1 in more than 6 cancer types. Because this analysis shows association rather than direction, both GOSR1-to-partner and partner-to-GOSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GOSR1 versus GIT1 in LSCC, with a Pearson correlation of 0.45.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GOSR1→partner) and Y-score (partner→GOSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GIT1 →	+0.207	+0.479	<.001	<.001	3	7
LSCC	LIG3 →	+0.524	+0.599	<.001	<.001	3	6
BRCA	RHOT1 →	+0.245	+0.318	<.001	<.001	3	5
HNSC	SUGP2 →	+0.379	+0.443	.002	<.001	3	5
GBM	BUB3 →	+0.257	+0.272	.007	.003	3	5
GBM	CSTF1 →	+0.197	+0.231	.004	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,924 associations by consensus.

GOSR1 vs GIT1 — LSCC

Explore this scatter interactively →