GOSR1

Across TCGA patient cohorts, GOSR1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,930 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GOSR1-associated genes across cancer lineages are COL14A1, PSMB3, and RECK. Each is linked with GOSR1 in more than 5 cancer types. Because this analysis shows association rather than direction, both GOSR1-to-partner and partner-to-GOSR1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GOSR1 versus COL14A1 in CCRCC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOSR1→partner) and Y-score (partner→GOSR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	COL14A1 →	-1.020	-0.180	.001	.001	3	5
LSCC	PSMB3 →	+0.590	+0.284	<.001	<.001	3	5
CCRCC	RECK →	-0.604	-0.209	<.001	<.001	3	5
HNSC	NES →	-1.037	-0.208	<.001	<.001	3	5
UCEC	GYPC →	-0.831	-0.268	<.001	.002	3	5
BRCA	SLC25A27 →	-0.991	-0.395	.001	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,930 associations by consensus.

GOSR1 vs COL14A1 — CCRCC

Explore this scatter interactively →