GORASP2

Across TCGA cell cohorts, GORASP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,086 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GORASP2-associated GO terms across cancer lineages are Regulation of translation initiation in response to endoplasmic reticulum stress, Negative regulation of endoplasmic reticulum unfolded protein response, and Endoplasmic reticulum to cytosol transport. Each is linked with GORASP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both GORASP2-to-partner and partner-to-GORASP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of translation initiation in response to endoplasmic reticulum stress grouped by GORASP2-low versus GORASP2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GORASP2→partner) and Y-score (partner→GORASP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of translation initiation in response to endoplasmic reticulum stress →	+0.117	+0.623	<.001	<.001	3	11
BLOOD_Lymphoma	Negative regulation of endoplasmic reticulum unfolded protein response →	+0.105	+0.807	<.001	.002	3	10
BLOOD_Lymphoma	Endoplasmic reticulum to cytosol transport →	+0.117	+0.730	<.001	.001	3	10
BLOOD_Lymphoma	Retrograde protein transport, ER to cytosol →	+0.117	+0.730	<.001	.001	3	10
BLOOD_Leukemia	Regulation of chromatin organization →	+0.078	+0.611	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Regulation of stress-activated protein kinase signaling cascade →	+0.073	+0.684	.009	.008	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,086 associations by consensus.

Regulation of translation initiation in response to endoplasmic reticulum stress by GORASP2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →