GOPC

Across TCGA patient cohorts, GOPC RNA expression is significantly associated with the protein abundance of many other proteins, with 11,502 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GOPC-associated proteins across cancer lineages are GPX7, PPIF, and PPIL4. Each is linked with GOPC in more than 4 cancer types. Because this analysis shows association rather than direction, both GOPC-to-partner and partner-to-GOPC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GOPC versus GPX7 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GOPC→partner) and Y-score (partner→GOPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GPX7 →	+0.579	+0.524	.002	.001	3	5
OV	PPIF →	-0.521	-0.553	.005	.003	3	5
LSCC	PPIL4 →	+0.207	+0.352	<.001	<.001	3	5
GBM	ARID1B →	+0.187	+0.467	<.001	<.001	3	5
BRCA	C1QTNF5 →	+0.628	+0.417	.001	.001	3	4
BRCA	COL5A2 →	+0.639	+0.384	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,502 associations by consensus.

GOPC vs GPX7 — OV

Explore this scatter interactively →