GON7

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GON7 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,036 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GON7-associated proteins across cancer lineages are UBR7, PPP4R3A, and SETD3. Each is linked with GON7 in more than 6 cancer types. Because this analysis shows association rather than direction, both GON7-to-partner and partner-to-GON7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GON7 versus UBR7 in GBM, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GON7→partner) and Y-score (partner→GON7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMUBR7 →+0.468+0.382<.001<.00137
OVPPP4R3A →+0.398+0.678.005.00237
OVSETD3 →+0.279+0.634<.001<.00136
LSCCBAG5 →+0.312+0.612.001<.00135
COADCEP170B →+0.376+0.652<.001<.00135
OVGSTZ1 →+0.625+0.856<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,036 associations by consensus.

GON7 vs UBR7 — GBM

Per-sample scatter of GON7 vs UBR7 in GBM (Pearson r = 0.42).

Explore this scatter interactively →

Exploration