GOLPH3L

Across TCGA patient cohorts, GOLPH3L protein abundance is significantly associated with the RNA expression of many other genes, with 15,610 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GOLPH3L-associated genes across cancer lineages are PPP1R18, TJP3, and LRRC31. Each is linked with GOLPH3L in more than 6 cancer types. Because this analysis shows association rather than direction, both GOLPH3L-to-partner and partner-to-GOLPH3L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GOLPH3L versus PPP1R18 in COAD, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLPH3L→partner) and Y-score (partner→GOLPH3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	PPP1R18 →	-0.992	-0.431	<.001	<.001	3	7
BRCA	TJP3 →	+1.068	+0.344	<.001	.003	3	6
LUAD	LRRC31 →	+1.792	+0.411	<.001	<.001	3	6
HNSC	MFSD12 →	-0.649	-0.471	.001	<.001	3	6
COAD	CAVIN1 →	-1.226	-0.369	<.001	<.001	3	6
PDAC	SNAI2 →	-0.925	-0.446	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,610 associations by consensus.

GOLPH3L vs PPP1R18 — COAD

Explore this scatter interactively →