GOLPH3L

Across TCGA cell cohorts, GOLPH3L RNA expression is significantly associated with the go_rna of many other GO terms, with 3,506 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLPH3L-associated GO terms across cancer lineages are Protein targeting to Golgi apparatus, Golgi vesicle budding, and Post-Golgi vesicle-mediated transport. Each is linked with GOLPH3L in more than 19 cancer types. Because this analysis shows association rather than direction, both GOLPH3L-to-partner and partner-to-GOLPH3L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein targeting to Golgi apparatus grouped by GOLPH3L-low versus GOLPH3L-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLPH3L→partner) and Y-score (partner→GOLPH3L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Protein targeting to Golgi apparatus →	+0.225	+1.486	<.001	<.001	3	20
STOMACH	Golgi vesicle budding →	+0.160	+0.854	<.001	<.001	3	12
OVARY	Post-Golgi vesicle-mediated transport →	+0.048	+0.789	.002	.001	3	12
STOMACH	Vesicle budding from membrane →	+0.085	+0.855	.006	.007	2	13
BREAST	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.210	+0.681	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Golgi vesicle transport →	+0.064	+1.299	.004	.003	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,506 associations by consensus.

Protein targeting to Golgi apparatus by GOLPH3L expression — BLOOD_Myeloma

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