GOLPH3

Across TCGA patient cohorts, GOLPH3 protein abundance is significantly associated with the RNA expression of many other genes, with 10,902 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible GOLPH3-associated genes across cancer lineages are DAP, CLPTM1L, and C5orf22. Each is linked with GOLPH3 in more than 7 cancer types. Because this analysis shows association rather than direction, both GOLPH3-to-partner and partner-to-GOLPH3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GOLPH3 versus DAP in OV, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLPH3→partner) and Y-score (partner→GOLPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	DAP →	+0.613	+0.469	<.001	<.001	3	8
HNSC	CLPTM1L →	+0.559	+0.275	<.001	<.001	3	6
HNSC	C5orf22 →	+0.876	+0.377	<.001	<.001	3	6
CCRCC	THY1 →	-0.864	-0.295	<.001	<.001	3	5
CCRCC	KDELR3 →	+1.161	+0.391	<.001	<.001	3	5
COAD	PIGR →	+2.999	+0.313	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,902 associations by consensus.

GOLPH3 vs DAP — OV

Explore this scatter interactively →