GOLPH3

Across TCGA cell cohorts, GOLPH3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,998 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GOLPH3-associated GO terms across cancer lineages are Response to rapamycin, Cellular response to rapamycin, and Cell adhesion molecule production. Each is linked with GOLPH3 in more than 18 cancer types. Because this analysis shows association rather than direction, both GOLPH3-to-partner and partner-to-GOLPH3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to rapamycin grouped by GOLPH3-low versus GOLPH3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLPH3→partner) and Y-score (partner→GOLPH3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Response to rapamycin →	+0.212	+0.706	<.001	.003	3	19
STOMACH	Cellular response to rapamycin →	+0.201	+0.686	<.001	<.001	2	19
URINARY_TRACT	Cell adhesion molecule production →	+0.168	+0.797	<.001	<.001	3	15
URINARY_TRACT	Cellular response to ether →	+0.183	+0.692	.007	.004	3	15
LIVER	Replication-born double-strand break repair via sister chromatid exchange →	+0.227	+0.750	.005	.007	3	14
SKIN	Establishment of mitotic sister chromatid cohesion →	+0.093	+0.635	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,998 associations by consensus.

Response to rapamycin by GOLPH3 expression — LIVER

Explore this box plot interactively →