GOLM2

Across TCGA pan-cancer cohorts, GOLM2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated GOLM2 data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher GOLM2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GOLM2 expression acts as an unfavorable survival marker.

LSCC, CCRCC, and LUAD are the cancer types where GOLM2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Tertile	II,III,IV	0.576	0.944	.006	28	view →
CCRCC	OS	Median	All	0.664	1.000	.009	21	view →
LUAD	DFS	Median	II,III,IV	0.778	0.928	.016	8	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

GOLM2–LSCC (OS)

Open the LSCC breakdown →