GOLM2

Across TCGA cell cohorts, GOLM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,462 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GOLM2-associated GO terms across cancer lineages are Macroautophagy, Process utilizing autophagic mechanism, and Post-Golgi vesicle-mediated transport. Each is linked with GOLM2 in more than 14 cancer types. Because this analysis shows association rather than direction, both GOLM2-to-partner and partner-to-GOLM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macroautophagy grouped by GOLM2-low versus GOLM2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLM2→partner) and Y-score (partner→GOLM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Macroautophagy →	+0.074	+1.119	<.001	.003	3	15
BONE	Process utilizing autophagic mechanism →	+0.067	+0.952	.001	.001	3	14
BONE	Post-Golgi vesicle-mediated transport →	+0.079	+0.916	<.001	<.001	3	14
BONE	Autophagy →	+0.067	+0.952	.001	.001	3	14
BONE	Protein demannosylation →	+0.117	+0.727	<.001	<.001	3	13
BONE	Protein alpha-1,2-demannosylation →	+0.117	+0.727	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,462 associations by consensus.

Macroautophagy by GOLM2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →