GOLM1

Across TCGA patient cohorts, GOLM1 mutation is significantly associated with the RNA expression of many other genes, with 696 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLM1-associated genes across cancer lineages are RNU6-1144P, RNA5SP414, and ANKRD49P3. Each is linked with GOLM1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLM1-to-partner and partner-to-GOLM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1144P grouped by GOLM1-low versus GOLM1-high in PRAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLM1→partner) and Y-score (partner→GOLM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PRAD	RNU6-1144P →	+0.383	+7.939	<.001	.008	3	2
UCEC	RNA5SP414 →	+0.441	+2.032	.001	.007	3	2
CESC	ANKRD49P3 →	+0.060	+5.103	<.001	.008	3	2
CESC	DEFB127 →	+0.114	+6.342	<.001	.001	3	2
HNSC	MTCYBP19 →	+0.090	+4.270	<.001	.008	3	2
PRAD	RNU6-1116P →	+0.398	+7.939	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 696 associations by consensus.

RNU6-1144P by GOLM1 expression — PRAD

Explore this box plot interactively →