GOLIM4

Across TCGA pan-cancer cohorts, GOLIM4 Mutation is linked to patient survival in 4 of 34 cancer types, making it a survival-associated GOLIM4 data layer compared with 26 for mass-spec protein and 4 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher GOLIM4 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GOLIM4 expression acts as an unfavorable survival marker, although some lineages such as LUSC and SKCM show a favorable association.

KIRP, UCEC, and LUSC are the cancer types where GOLIM4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	OS	Median	All	0.176	0.885	<.001	24	view →
UCEC	OS	Median	IV	0.100	0.781	<.001	12	view →
LUSC	DFS	Median	All	1.000	0.382	.026	2	view →
SKCM	OS	Median	II,III,IV	1.000	0.830	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

GOLIM4–KIRP (OS)

Open the KIRP breakdown →