GOLIM4

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLIM4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,806 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GOLIM4-associated genes across cancer lineages are FKBP14, FNDC3B, and NKX3-2. Each is linked with GOLIM4 in more than 6 cancer types. Because this analysis shows association rather than direction, both GOLIM4-to-partner and partner-to-GOLIM4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GOLIM4 versus FKBP14 in OV, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLIM4→partner) and Y-score (partner→GOLIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVFKBP14 →+0.717+0.384.008.00427
HNSCFNDC3B →+0.685+0.355.001<.00136
OVNKX3-2 →+0.947+0.369<.001.00235
OVCOL10A1 →+2.269+0.507.001<.00135
HNSCSULF1 →+1.204+0.386<.001<.00135
OVMETTL11B →+0.624+0.369<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,806 associations by consensus.

GOLIM4 vs FKBP14 — OV

Per-sample scatter of GOLIM4 vs FKBP14 in OV (Pearson r = 0.31).

Explore this scatter interactively →

Exploration