GOLIM4

Across TCGA cell cohorts, GOLIM4 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GOLIM4-associated genes across cancer lineages are OR10W1, OR52H1, and OR52A1. Each is linked with GOLIM4 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLIM4-to-partner and partner-to-GOLIM4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by GOLIM4-low versus GOLIM4-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLIM4→partner) and Y-score (partner→GOLIM4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.012	+3.240	<.001	.004	3	1
LARGE_INTESTINE	OR52H1 →	+0.022	+3.084	<.001	.002	3	1
LARGE_INTESTINE	OR52A1 →	+0.007	+3.084	<.001	.002	3	1
LARGE_INTESTINE	SPEM2 →	+0.044	+4.211	.003	<.001	3	1
LARGE_INTESTINE	ZNF705A →	+0.017	+3.141	.001	.002	3	1
LARGE_INTESTINE	CCER1 →	+0.008	+3.240	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

OR10W1 by GOLIM4 expression — LARGE_INTESTINE

Explore this box plot interactively →