GOLGB1

Across TCGA pan-cancer cohorts, GOLGB1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GOLGB1 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GOLGB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GOLGB1 expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, LSCC, and UCEC are the cancer types where GOLGB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	All	1.000	0.885	.018	48	view →
LSCC	OS	Tertile	All	0.622	0.907	.004	23	view →
UCEC	DFS	Quartile	II,III,IV	0.853	0.328	.033	12	view →
HNSC	DFS	Quartile	All	0.891	0.708	.029	7	view →
LUAD	OS	Tertile	III,IV	0.743	0.247	.006	6	view →
PDAC	OS	Tertile	III,IV	1.000	0.328	.013	2	view →
CCRCC	DFS	Tertile	III,IV	0.221	1.000	.049	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GOLGB1–COAD (DFS)

Open the COAD breakdown →