GOLGB1

Across TCGA patient cohorts, GOLGB1 mutation is significantly associated with the RNA expression of many other genes, with 8,672 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGB1-associated genes across cancer lineages are DCLRE1B, STIL, and SIKE1. Each is linked with GOLGB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GOLGB1-to-partner and partner-to-GOLGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DCLRE1B grouped by GOLGB1-low versus GOLGB1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGB1→partner) and Y-score (partner→GOLGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DCLRE1B →	+0.658	+1.960	<.001	<.001	3	5
COAD	STIL →	+0.654	+3.598	<.001	.001	3	5
UCEC	SIKE1 →	+0.380	+1.403	<.001	<.001	3	5
STAD	KRR1 →	+0.568	+3.338	<.001	.004	3	5
UCEC	MCM3 →	+0.473	+2.158	<.001	<.001	3	5
STAD	BUB3 →	+0.566	+2.923	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,672 associations by consensus.

DCLRE1B by GOLGB1 expression — UCEC

Explore this box plot interactively →