GOLGB1

Across TCGA patient cohorts, GOLGB1 mutation is significantly associated with the total protein of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGB1-associated genes across cancer lineages are Caspase-7-cleavedD198, ER-alpha, and PCNA. Each is linked with GOLGB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GOLGB1-to-partner and partner-to-GOLGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by GOLGB1-low versus GOLGB1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGB1→partner) and Y-score (partner→GOLGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.886	+1.874	.002	.049	3	5
CESC	ER-alpha →	-0.630	-3.584	.019	.002	3	4
UCEC	PCNA →	+0.190	+2.392	<.001	<.001	3	4
COAD	INPP4B →	-0.344	-2.584	.013	.010	3	4
UCEC	ASNS →	+0.264	+1.263	.004	.016	3	3
UCEC	c-Met_pY1235 →	+0.038	+0.912	.046	.032	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Caspase-7-cleavedD198 by GOLGB1 expression — COAD

Explore this box plot interactively →