GOLGB1

Across TCGA cell cohorts, GOLGB1 mutation is significantly associated with the RNA expression of many other genes, with 604 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GOLGB1-associated genes across cancer lineages are RAB40B, KCNJ11, and TAS2R39. Each is linked with GOLGB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GOLGB1-to-partner and partner-to-GOLGB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAB40B grouped by GOLGB1-low versus GOLGB1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGB1→partner) and Y-score (partner→GOLGB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RAB40B →	+0.749	+2.115	.002	.004	3	3
LARGE_INTESTINE	KCNJ11 →	+0.540	+1.807	.007	.005	3	3
OVARY	TAS2R39 →	+0.025	+3.405	<.001	.005	3	3
PANCREAS	SULT1C3 →	+0.169	+3.321	<.001	.001	3	2
PANCREAS	MYH4 →	+0.012	+3.584	<.001	.001	3	2
SOFT_TISSUE	FTMT →	+0.043	+3.977	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 604 associations by consensus.

RAB40B by GOLGB1 expression — LARGE_INTESTINE

Explore this box plot interactively →