GOLGA8N

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA8N mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA8N-associated genes across cancer lineages are POLR2J2, RNU7-125P, and LINC01995. Each is linked with GOLGA8N in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8N-to-partner and partner-to-GOLGA8N results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POLR2J2 grouped by GOLGA8N-low versus GOLGA8N-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8N→partner) and Y-score (partner→GOLGA8N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPOLR2J2 →+0.114+5.073<.001.00131
UCECRNU7-125P →+1.059+4.690<.001.00331
UCECLINC01995 →+0.464+5.474<.001<.00131
UCECMIR4285 →+0.627+4.473.002.00531
Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

POLR2J2 by GOLGA8N expression — UCEC

Box plot of POLR2J2 in GOLGA8N-low vs GOLGA8N-high samples in UCEC.

Explore this box plot interactively →

Exploration