GOLGA8N

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA8N mutation is significantly associated with the RNA expression of many other genes, with 42 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8N-associated genes across cancer lineages are TFCP2L1, CRYGD, and STATH. Each is linked with GOLGA8N in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8N-to-partner and partner-to-GOLGA8N results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFCP2L1 grouped by GOLGA8N-low versus GOLGA8N-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8N→partner) and Y-score (partner→GOLGA8N) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaTFCP2L1 →+1.196+3.233<.001.00931
BLOOD_LeukemiaCRYGD →+1.609+2.971<.001.00331
BLOOD_LeukemiaSTATH →+0.195+2.870<.001.00531
BLOOD_LeukemiaPLAAT1 →+0.871+3.559.009.00531
BLOOD_LeukemiaSFTPD →+0.198+4.025.002.00131
BLOOD_LeukemiaCYP2J2 →+0.654+3.233.004.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

TFCP2L1 by GOLGA8N expression — BLOOD_Leukemia

Box plot of TFCP2L1 in GOLGA8N-low vs GOLGA8N-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration