Across TCGA pan-cancer cohorts, GOLGA8J RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of GOLGA8J’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where GOLGA8J RNA is repressed in tumor relative to normal tissue. In most cancer types GOLGA8J is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA are the cancer types where GOLGA8J tumor–normal differential expression is most reproducible.