Across TCGA pan-cancer cohorts, GOLGA8DP RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GOLGA8DP’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where GOLGA8DP RNA is repressed in tumor relative to normal tissue. In most cancer types GOLGA8DP is over-expressed in tumor, although a few such as BRCA show the opposite, repressed pattern.
BRCA, HNSC, and LUSC are the cancer types where GOLGA8DP tumor–normal differential expression is most reproducible.