GOLGA8B

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA8B mutation is significantly associated with the RNA expression of many other genes, with 618 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA8B-associated genes across cancer lineages are MAP3K4-AS1, RNA5SP414, and MIR7702. Each is linked with GOLGA8B in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8B-to-partner and partner-to-GOLGA8B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8B→partner) and Y-score (partner→GOLGA8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMAP3K4-AS1 →+0.879+3.467<.001.00231
UCECRNA5SP414 →+0.594+2.670<.001.00131
UCECMIR7702 →+0.245+4.360<.001.00431
UCECZNF280B →+0.567+2.711.002.00331
UCECFCGBP →-1.370-3.443<.001.00531
UCECRNA5SP411 →+1.173+2.586<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 618 associations by consensus.

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