GOLGA8B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA8B mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible GOLGA8B-associated genes across cancer lineages are CBLL2, SPAG11A, and OR11G2. Each is linked with GOLGA8B in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8B-to-partner and partner-to-GOLGA8B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8B→partner) and Y-score (partner→GOLGA8B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaCBLL2 →+0.018+4.867<.001.00931
BLOOD_LymphomaSPAG11A →+0.080+4.867<.001.00931
BLOOD_LymphomaOR11G2 →+0.016+4.867<.001.00931
LUNG_SCLCUSP29 →+0.014+3.523<.001.00831
LUNG_SCLCS100G →+0.072+4.058<.001.00731
LUNG_SCLCMBD3L1 →+0.036+4.058<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration