GOLGA8A

Across TCGA patient cohorts, GOLGA8A mutation is significantly associated with the RNA expression of many other genes, with 1,654 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA8A-associated genes across cancer lineages are SSU72P8, RN7SL134P, and IL9. Each is linked with GOLGA8A in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8A-to-partner and partner-to-GOLGA8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SSU72P8 grouped by GOLGA8A-low versus GOLGA8A-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8A→partner) and Y-score (partner→GOLGA8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	SSU72P8 →	+1.057	+6.144	<.001	.001	3	2
UCEC	RN7SL134P →	+0.168	+2.706	<.001	<.001	3	2
UCEC	IL9 →	+0.088	+2.162	<.001	.004	3	2
UCEC	TAF11L12 →	+0.244	+1.911	.006	.005	3	2
CESC	LYZL1 →	+0.056	+5.418	<.001	.005	3	1
CESC	TRIM51 →	+0.852	+5.010	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,654 associations by consensus.

SSU72P8 by GOLGA8A expression — CESC

Explore this box plot interactively →