GOLGA8A

Across TCGA cell cohorts, GOLGA8A mutation is significantly associated with the RNA expression of many other genes, with 59 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GOLGA8A-associated genes across cancer lineages are CCDC182, SYT10, and PROP1. Each is linked with GOLGA8A in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA8A-to-partner and partner-to-GOLGA8A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC182 grouped by GOLGA8A-low versus GOLGA8A-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA8A→partner) and Y-score (partner→GOLGA8A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CCDC182 →	+0.025	+4.285	<.001	.007	3	2
LARGE_INTESTINE	SYT10 →	+0.217	+2.518	<.001	.006	3	2
LARGE_INTESTINE	PROP1 →	+0.025	+3.054	<.001	.001	3	2
PANCREAS	PTH2 →	+0.131	+5.000	<.001	.006	3	1
BREAST	TSPY2 →	+0.026	+5.781	<.001	.001	3	1
BREAST	TSPY10 →	+0.026	+5.781	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

CCDC182 by GOLGA8A expression — STOMACH

Explore this box plot interactively →