GOLGA7

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GOLGA7 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GOLGA7 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GOLGA7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GOLGA7 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

COAD, HNSC, and CCRCC are the cancer types where GOLGA7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSQuartileAll0.7941.000.01178view →
HNSCDFSTertileII,III,IV0.8130.503.00328view →
CCRCCDFSTertileIII,IV0.1980.887.01019view →
PDACDFSQuartileAll0.1740.410.00716view →
LSCCDFSMedianII,III,IV1.0000.840.00713view →
UCECOSMedianAll0.9870.906.0276view →
GBMOSMedianAll0.2390.540.0164view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GOLGA7–COAD (DFS)

Kaplan–Meier survival curve for GOLGA7 mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration