GOLGA7

Across TCGA pan-cancer cohorts, GOLGA7 mass-spec protein differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of GOLGA7’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where GOLGA7 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types GOLGA7 is over-expressed in tumor, although a few such as PDAC and LUAD show the opposite, repressed pattern.

LSCC, COAD, and PDAC are the cancer types where GOLGA7 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GOLGA7 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LSCC	Male	All	+0.637	<.001	8	view →
COAD	Female	IV	+1.033	.040	1	view →
PDAC	Male	All	−0.324	.023	1	view →
HNSC	Male	II,III,IV	+0.139	.048	1	view →
LUAD	Female	All	−0.135	.016	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

GOLGA7–LSCC

Open the LSCC breakdown →