GOLGA7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA7 mutation is significantly associated with the RNA expression of many other genes, with 1,180 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA7-associated genes across cancer lineages are RNA5SP252, RNA5SP356, and RNA5SP495. Each is linked with GOLGA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA7-to-partner and partner-to-GOLGA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP252 grouped by GOLGA7-low versus GOLGA7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA7→partner) and Y-score (partner→GOLGA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP252 →+0.595+2.840<.001.00432
SKCMRNA5SP356 →+0.247+7.816<.001.00832
SKCMRNA5SP495 →+0.213+7.816<.001.00832
SKCMMTND3P6 →+0.079+7.816<.001.00831
CESCRPL7AP72 →+0.051+5.969<.001.00231
CESCMTCO3P41 →+0.165+6.342<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,180 associations by consensus.

RNA5SP252 by GOLGA7 expression — UCEC

Box plot of RNA5SP252 in GOLGA7-low vs GOLGA7-high samples in UCEC.

Explore this box plot interactively →

Exploration