GOLGA7

Across TCGA patient cohorts, GOLGA7 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA7-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and GAPDH. Each is linked with GOLGA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA7-to-partner and partner-to-GOLGA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by GOLGA7-low versus GOLGA7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA7→partner) and Y-score (partner→GOLGA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.331	-3.584	.006	.002	3	1
UCEC	eIF4E →	+0.240	+3.013	.018	.018	3	1
UCEC	GAPDH →	+0.557	+3.169	.031	.018	3	1
UCEC	mTOR_pS2448 →	-0.249	-3.446	<.001	.005	3	1
UCEC	Notch1 →	+0.283	+2.331	<.001	.019	3	1
UCEC	Shc_pY317 →	-0.186	-3.169	.011	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

EGFR_pY1068 by GOLGA7 expression — UCEC

Explore this box plot interactively →