GOLGA6L7

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA6L7 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA6L7-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and ERK2. Each is linked with GOLGA6L7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6L7-to-partner and partner-to-GOLGA6L7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by GOLGA6L7-low versus GOLGA6L7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6L7→partner) and Y-score (partner→GOLGA6L7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECATM →-0.758-2.986.001.03531
UCECCaspase-7-cleavedD198 →+0.874+2.827.004.03531
UCECERK2 →+0.328+3.321.001.01011
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ATM by GOLGA6L7 expression — UCEC

Box plot of ATM in GOLGA6L7-low vs GOLGA6L7-high samples in UCEC.

Explore this box plot interactively →

Exploration