GOLGA6L22

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GOLGA6L22 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated GOLGA6L22 data layer compared with 13 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher GOLGA6L22 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GOLGA6L22 expression acts as an unfavorable survival marker.

ESCA and SARC are the cancer types where GOLGA6L22 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCAOSMedianII,III,IV0.1640.702.00121view →
SARCDFSMedianAll0.1090.632.0383view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

GOLGA6L22–ESCA (OS)

Kaplan–Meier survival curve for GOLGA6L22 mutant vs wild-type samples in ESCA.

Open the ESCA breakdown →

Exploration