GOLGA6L2

Across TCGA patient cohorts, GOLGA6L2 mutation is significantly associated with the RNA expression of many other genes, with 1,751 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA6L2-associated genes across cancer lineages are SNX3P1Y, RPL12P5, and RNU6-206P. Each is linked with GOLGA6L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6L2-to-partner and partner-to-GOLGA6L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNX3P1Y grouped by GOLGA6L2-low versus GOLGA6L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6L2→partner) and Y-score (partner→GOLGA6L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNX3P1Y →	+0.060	+3.723	<.001	.008	3	2
SKCM	RPL12P5 →	+0.065	+4.282	<.001	.009	3	2
UCEC	RNU6-206P →	+0.104	+3.129	<.001	.004	3	2
UCEC	COBLP1 →	+0.156	+1.387	<.001	.008	3	2
UCEC	RNU6-927P →	+0.201	+2.590	<.001	<.001	3	2
UCEC	RN7SL147P →	+0.113	+2.103	.005	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,751 associations by consensus.

SNX3P1Y by GOLGA6L2 expression — UCEC

Explore this box plot interactively →