GOLGA6L2

Across TCGA patient cohorts, GOLGA6L2 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA6L2-associated genes across cancer lineages are PDCD4, TIGAR, and EGFR_pY1068. Each is linked with GOLGA6L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6L2-to-partner and partner-to-GOLGA6L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDCD4 grouped by GOLGA6L2-low versus GOLGA6L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6L2→partner) and Y-score (partner→GOLGA6L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.609	-1.925	<.001	.005	3	2
UCEC	TIGAR →	+0.130	+1.906	.018	.015	3	2
UCEC	EGFR_pY1068 →	-0.218	-3.459	.015	.005	3	1
UCEC	FOXO3a_pS318_S321 →	-0.139	-2.405	.001	.003	3	1
UCEC	JNK2 →	+0.225	+1.584	.001	.019	3	1
UCEC	Ku80 →	+0.217	+1.598	.010	.040	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

PDCD4 by GOLGA6L2 expression — UCEC

Explore this box plot interactively →