GOLGA6L2

Across TCGA cell cohorts, GOLGA6L2 mutation is significantly associated with the RNA expression of many other genes, with 433 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GOLGA6L2-associated genes across cancer lineages are OR1L6, LY86, and TMEM132C. Each is linked with GOLGA6L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA6L2-to-partner and partner-to-GOLGA6L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR1L6 grouped by GOLGA6L2-low versus GOLGA6L2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA6L2→partner) and Y-score (partner→GOLGA6L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR1L6 →	+0.016	+3.727	<.001	.002	3	2
LARGE_INTESTINE	LY86 →	+0.042	+2.380	.002	.004	3	2
LUNG_NSCLC_LUSC	TMEM132C →	+0.122	+3.584	.003	.003	3	1
SOFT_TISSUE	IFNK →	+0.027	+3.297	<.001	.008	3	1
SOFT_TISSUE	CD1C →	+0.054	+3.142	.001	.008	3	1
SOFT_TISSUE	PYDC1 →	+0.436	+3.597	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 433 associations by consensus.

OR1L6 by GOLGA6L2 expression — BREAST

Explore this box plot interactively →