GOLGA6C

Across TCGA pan-cancer cohorts, GOLGA6C RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated GOLGA6C data layer compared with 3 for mutation status.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher GOLGA6C RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated GOLGA6C expression acts as an unfavorable survival marker, although some lineages such as LIHC and SKCM show a favorable association.

ESCA, HNSC, and KIRC are the cancer types where GOLGA6C RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	DFS	Tertile	All	0.314	0.586	<.001	147	view →
HNSC	OS	Tertile	II,III,IV	0.185	0.716	<.001	120	view →
KIRC	OS	Tertile	All	0.464	0.663	<.001	114	view →
COAD	DFS	Tertile	III,IV	0.354	0.671	<.001	93	view →
KICH	DFS	Tertile	II,III,IV	0.043	0.950	<.001	90	view →
UCS	DFS	Tertile	IV	0.132	0.718	.002	54	view →
THCA	DFS	Tertile	All	0.830	0.949	.005	45	view →
UCEC	DFS	Tertile	IV	0.136	0.729	<.001	36	view →
UVM	DFS	Tertile	All	0.079	0.746	<.001	36	view →
CESC	DFS	Tertile	II,III,IV	0.184	0.705	.036	36	view →
LUAD	DFS	Tertile	IV	0.109	0.714	.001	36	view →
THYM	OS	Tertile	All	0.524	0.901	.003	27	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

GOLGA6C–ESCA (DFS)

Open the ESCA breakdown →