GOLGA5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA5 mutation is significantly associated with the RNA expression of many other genes, with 4,248 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA5-associated genes across cancer lineages are DLST, OR7E149P, and GAPDHP56. Each is linked with GOLGA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both GOLGA5-to-partner and partner-to-GOLGA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DLST grouped by GOLGA5-low versus GOLGA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA5→partner) and Y-score (partner→GOLGA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECDLST →+0.455+2.321<.001<.00133
BRCAOR7E149P →+0.041+5.148.002.00832
BRCAGAPDHP56 →+0.037+6.505.006.00132
SKCMRNU6-136P →+0.368+4.177.003.00432
CESCRNA5SP492 →+0.466+4.320<.001.00732
BRCARNU6-264P →+0.733+5.070<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,248 associations by consensus.

DLST by GOLGA5 expression — UCEC

Box plot of DLST in GOLGA5-low vs GOLGA5-high samples in UCEC.

Explore this box plot interactively →

Exploration