GOLGA5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GOLGA5 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GOLGA5-associated genes across cancer lineages are FTMT, OR2L8, and TMEM196. Each is linked with GOLGA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GOLGA5-to-partner and partner-to-GOLGA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FTMT grouped by GOLGA5-low versus GOLGA5-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA5→partner) and Y-score (partner→GOLGA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEFTMT →+0.086+5.977<.001.00131
SOFT_TISSUEOR2L8 →+0.039+5.369<.001.00431
BLOOD_LeukemiaTMEM196 →+0.036+3.874<.001.00531
BLOOD_LeukemiaGSG1L2 →+0.034+4.384<.001.00631
LARGE_INTESTINENEU2 →+0.020+3.376.004.00231
LARGE_INTESTINEKCNK17 →+0.073+3.333<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

FTMT by GOLGA5 expression — SOFT_TISSUE

Box plot of FTMT in GOLGA5-low vs GOLGA5-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration