GOLGA4

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GOLGA4 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated GOLGA4 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher GOLGA4 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated GOLGA4 expression acts as an unfavorable survival marker, although some lineages such as COAD and PDAC show a favorable association.

COAD, PDAC, and LUAD are the cancer types where GOLGA4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSMedianII,III,IV1.0000.882.02154view →
PDACDFSMedianAll0.8510.676.00820view →
LUADOSMedianIII,IV0.8610.384.0304view →
CCRCCDFSMedianIII,IV0.4550.694.0363view →
GBMDFSQuartileAll0.6530.867.0232view →
HNSCDFSMedianIV0.8890.407.0422view →
LSCCDFSMedianAll0.6440.896.0441view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

GOLGA4–COAD (DFS)

Kaplan–Meier survival curve for GOLGA4 mass-spec protein-high vs -low samples in COAD.

Open the COAD breakdown →

Exploration