GOLGA4

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GOLGA4 mutation is significantly associated with the RNA expression of many other genes, with 3,966 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GOLGA4-associated genes across cancer lineages are RNU6-1013P, UBR7, and GLRX5. Each is linked with GOLGA4 in more than 3 cancer types. Because this analysis shows association rather than direction, both GOLGA4-to-partner and partner-to-GOLGA4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1013P grouped by GOLGA4-low versus GOLGA4-high in KIRP.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GOLGA4→partner) and Y-score (partner→GOLGA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPRNU6-1013P →+0.361+4.628<.001.00734
UCECUBR7 →+0.479+1.513<.001<.00134
COADGLRX5 →+0.338+3.499.006.00234
COADMRPL46 →+0.346+3.220.001.00934
UCECAAGAB →+0.449+2.042<.001<.00134
UCECPSMC3IP →+0.642+1.470<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,966 associations by consensus.

RNU6-1013P by GOLGA4 expression — KIRP

Box plot of RNU6-1013P in GOLGA4-low vs GOLGA4-high samples in KIRP.

Explore this box plot interactively →

Exploration